Thursday, December 23, 2010

Timeperiod Between Tb Testing

On the origin of the strain of Vibrio cholerae Cholera in Haiti

A study published last December 9 the site of the New England Journal of Medicine reports the results of investigations carried out on the genome of Vibrio cholerae isolates obtained during the outbreak currently underway on the island of Hispaniola (includes Haiti and the Dominican Republic).

Researchers compared the genomes of these strains with that of other strains isolated in various parts of the world.
E 'was found a close relationship between the island of Haiti and variant strains of V. cholerae El Tor 01 identified in Bangladesh in 2002 and 2008. The authors conclude that the epidemic in Haiti is probably the result of the introduction through human activities, of a strain of vibrio choleric from a geographically distant.

As you know, many Haitians have impeached the Nepalese soldiers sent to the country after the earthquake, according to a UN mandate. In fact, while it is true that the strain of V.cholerae working in Haiti is of South Asian, no one can tell from which country it comes from that area and how it got in ' island of Hispaniola. In fact the island after the earthquake, has come to staff from many organizations around the world and has not said that it is possible to trace the source of the infection.

In fact, instead of looking for the infector, it would be important to establish procedures
to prevent such incidents could happen again.
could be made an example of screening between
people coming from areas endemic for cholera when they are sent to the scene of a natural disaster, or presumptively could be given to those subject an antibiotic which V. cholerae is sensitive.

This study demonstrates once again the crucial role in the epidemiological context, technologies that allow genome analysis of bacteria and viruses responsible for epidemics.
Il testo integrale dell'articolo รจ disponibile nel sito web del NEJM:


Chin CS, Sorenson J, Harris JB, Robins WP, Charles RC, Jean-Charles RR, et al. The Origin of the Haitian Cholera Outbreak Strain. N Engl J Med. 2010 Dec 9.
doi 10.1056/NEJMoa1012928
http://www.nejm.org/doi/full/10.1056/NEJMoa1012928

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